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IGF-1 as a Potential Therapy for Spinocerebellar Ataxia Type 3

Although the effects of growth hormone (GH) therapy on spinocerebellar ataxia type 3 (SCA3) have been examined in transgenic SCA3 mice, it still poses a nonnegligible risk of cancer when used for a long term. This study investigated the efficacy of IGF-1, a downstream mediator of GH, in vivo for SCA...

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Detalles Bibliográficos
Autores principales: Lin, Yong-Shiou, Cheng, Wen-Ling, Chang, Jui-Chih, Lin, Ta-Tsung, Chao, Yi-Chun, Liu, Chin-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962315/
https://www.ncbi.nlm.nih.gov/pubmed/35203722
http://dx.doi.org/10.3390/biomedicines10020505