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The Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics

Mitochondria are intracellular organelles that utilize nutrients to generate energy in the form of ATP by oxidative phosphorylation. Mitochondrial DNA (mtDNA) in humans is a 16,569 base pair double-stranded circular DNA that encodes for 13 vital proteins of the electron transport chain. Our understa...

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Detalles Bibliográficos
Autores principales: Saravanan, Sanjana, Lewis, Caitlin J., Dixit, Bhavna, O’Connor, Matthew S., Stolzing, Alexandra, Boominathan, Amutha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962324/
https://www.ncbi.nlm.nih.gov/pubmed/35203698
http://dx.doi.org/10.3390/biomedicines10020490