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Loss of atm in Zebrafish as a Model of Ataxia–Telangiectasia Syndrome

Ataxia–telangiectasia mutated (ATM) is a key DNA damage signaling kinase that is mutated in humans with ataxia–telangiectasia (A-T) syndrome. This syndrome is characterized by neurodegeneration, immune abnormality, cancer predisposition, and premature aging. To better understand the function of ATM...

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Detalles Bibliográficos
Autores principales: Chen, Kehua, Wang, Peng, Chen, Jingrun, Ying, Yiling, Chen, Yi, Gilson, Eric, Lu, Yiming, Ye, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962326/
https://www.ncbi.nlm.nih.gov/pubmed/35203601
http://dx.doi.org/10.3390/biomedicines10020392