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In Vivo Evaluation of ECP Peptide Analogues for the Treatment of Acinetobacter baumannii Infection

Antimicrobial peptides (AMPs) are alternative therapeutics to traditional antibiotics against bacterial resistance. Our previous work identified an antimicrobial region at the N-terminus of the eosinophil cationic protein (ECP). Following structure-based analysis, a 30mer peptide (ECPep-L) was desig...

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Detalles Bibliográficos
Autores principales: Li, Jiarui, Prats-Ejarque, Guillem, Torrent, Marc, Andreu, David, Brandenburg, Klaus, Fernández-Millán, Pablo, Boix, Ester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962335/
https://www.ncbi.nlm.nih.gov/pubmed/35203595
http://dx.doi.org/10.3390/biomedicines10020386