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Neuron–Microglia Contacts Govern the PGE(2) Tolerance through TLR4-Mediated de Novo Protein Synthesis

Cellular and molecular mechanisms of the peripheral immune system (e.g., macrophage and monocyte) in programming endotoxin tolerance (ET) have been well studied. However, regulatory mechanism in development of brain immune tolerance remains unclear. The inducible COX-2/PGE(2) axis in microglia, the...

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Detalles Bibliográficos
Autores principales: Kuo, Hsing-Chun, Lee, Kam-Fai, Chen, Shiou-Lan, Chiu, Shu-Chen, Lee, Li-Ya, Chen, Wan-Ping, Chen, Chin-Chu, Chu, Chun-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962342/
https://www.ncbi.nlm.nih.gov/pubmed/35203628
http://dx.doi.org/10.3390/biomedicines10020419