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Neuron–Microglia Contacts Govern the PGE(2) Tolerance through TLR4-Mediated de Novo Protein Synthesis
Cellular and molecular mechanisms of the peripheral immune system (e.g., macrophage and monocyte) in programming endotoxin tolerance (ET) have been well studied. However, regulatory mechanism in development of brain immune tolerance remains unclear. The inducible COX-2/PGE(2) axis in microglia, the...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962342/ https://www.ncbi.nlm.nih.gov/pubmed/35203628 http://dx.doi.org/10.3390/biomedicines10020419 |