Purinergic Receptor P2Y2 Stimulation Averts Aortic Valve Interstitial Cell Calcification and Myofibroblastic Activation

Rationale—Calcific aortic valve stenosis (CAVS) is a pathological condition of the aortic valve with a prevalence of 3% in the general population. It is characterized by massive rearrangement of the extracellular matrix, mostly due to the accumulation of fibro-calcific deposits driven by valve inter...

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Detalles Bibliográficos
Autores principales: Moschetta, Donato, Di Maria, Enrico, Valerio, Vincenza, Massaiu, Ilaria, Bozzi, Michele, Songia, Paola, D’alessandra, Yuri, Myasoedova, Veronika A., Poggio, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962345/
https://www.ncbi.nlm.nih.gov/pubmed/35203666
http://dx.doi.org/10.3390/biomedicines10020457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962345/
https://www.ncbi.nlm.nih.gov/pubmed/35203666
http://dx.doi.org/10.3390/biomedicines10020457

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