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Purinergic Receptor P2Y2 Stimulation Averts Aortic Valve Interstitial Cell Calcification and Myofibroblastic Activation
Rationale—Calcific aortic valve stenosis (CAVS) is a pathological condition of the aortic valve with a prevalence of 3% in the general population. It is characterized by massive rearrangement of the extracellular matrix, mostly due to the accumulation of fibro-calcific deposits driven by valve inter...
Autores principales: | Moschetta, Donato, Di Maria, Enrico, Valerio, Vincenza, Massaiu, Ilaria, Bozzi, Michele, Songia, Paola, D’alessandra, Yuri, Myasoedova, Veronika A., Poggio, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962345/ https://www.ncbi.nlm.nih.gov/pubmed/35203666 http://dx.doi.org/10.3390/biomedicines10020457 |
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