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Minimum Effective Dose of DPP-4 Inhibitors for Treating Early Stages of Diabetic Retinopathy in an Experimental Model

The neurovascular unit (NVU) plays an essential role in the development of diabetic retinopathy (DR). We previously reported that the topical administration (eye drops) of sitagliptin and saxagliptin, two dipeptidyl peptidase-4 inhibitors (DPP-4i), prevents retinal neurodegeneration and vascular lea...

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Detalles Bibliográficos
Autores principales: Bogdanov, Patricia, Ramos, Hugo, Valeri, Marta, Deàs-Just, Anna, Huerta, Jordi, Simó, Rafael, Hernández, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962353/
https://www.ncbi.nlm.nih.gov/pubmed/35203674
http://dx.doi.org/10.3390/biomedicines10020465