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AAV-Vectored Expression of the Vascular Normalizing Agents 3TSR and Fc3TSR, and the Anti-Angiogenic Bevacizumab Extends Survival in a Murine Model of End-Stage Epithelial Ovarian Carcinoma

Epithelial ovarian cancer is the deadliest gynecological malignancy. The lack of effective treatments highlights the need for novel therapeutic interventions. The aim of this study was to investigate whether sustained adeno-associated virus (AAV) vector-mediated expression of vascular normalizing ag...

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Detalles Bibliográficos
Autores principales: Stegelmeier, Ashley A., Santry, Lisa A., Guilleman, Matthew M., Matuszewska, Kathy, Minott, Jessica A., Yates, Jacob G. E., Stevens, Brenna A. Y., Thomas, Sylvia P., Vanderkamp, Sierra, Hanada, Kiersten, Pei, Yanlong, Rghei, Amira D., van Vloten, Jacob P., Pereira, Madison, Thompson, Brad, Major, Pierre P., Petrik, James J., Bridle, Byram W., Wootton, Sarah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962366/
https://www.ncbi.nlm.nih.gov/pubmed/35203573
http://dx.doi.org/10.3390/biomedicines10020362