Aripiprazole Offsets Mutant ATXN3-Induced Motor Dysfunction by Targeting Dopamine D(2) and Serotonin 1A and 2A Receptors in C. elegans

The atypical antipsychotic aripiprazole is a Food and Drug Administration-approved drug for the treatment of psychotic, mood, and other psychiatric disorders. Previous drug discovery efforts pinpointed aripiprazole as an effective suppressor of Machado–Joseph disease (MJD) pathogenesis, as its admin...

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Detalles Bibliográficos
Autores principales: Jalles, Ana, Vieira, Cármen, Pereira-Sousa, Joana, Vilasboas-Campos, Daniela, Mota, Ana Francisca, Vasconcelos, Sara, Ferreira-Lomba, Bruna, Costa, Marta Daniela, Da Silva, Jorge Diogo, Maciel, Patrícia, Teixeira-Castro, Andreia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962381/
https://www.ncbi.nlm.nih.gov/pubmed/35203579
http://dx.doi.org/10.3390/biomedicines10020370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962381/
https://www.ncbi.nlm.nih.gov/pubmed/35203579
http://dx.doi.org/10.3390/biomedicines10020370

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