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Drug Design Targeting the Muscarinic Receptors and the Implications in Central Nervous System Disorders

There is substantial evidence that cholinergic system function impairment plays a significant role in many central nervous system (CNS) disorders. During the past three decades, muscarinic receptors (mAChRs) have been implicated in various pathologies and have been prominent targets of drug-design e...

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Detalles Bibliográficos
Autores principales: Johnson, Chad R., Kangas, Brian D., Jutkiewicz, Emily M., Bergman, Jack, Coop, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962391/
https://www.ncbi.nlm.nih.gov/pubmed/35203607
http://dx.doi.org/10.3390/biomedicines10020398