Development of a High-Throughput Calcium Mobilization Assay for CCR6 Receptor Coupled to Hydrolase Activity Readout

CCR6 is a chemokine receptor highly implicated in inflammatory diseases and could be a potential therapeutic target; however, no therapeutic agents targeting CCR6 have progressed into clinical evaluation. Development of a high-throughput screening assay for CCR6 should facilitate the identification...

Descripción completa

Detalles Bibliográficos
Autores principales: Gómez-Melero, Sara, García-Maceira, Fé Isabel, García-Maceira, Tania, Luna-Guerrero, Verónica, Montero-Peñalvo, Gracia, Caballero-Villarraso, Javier, Túnez, Isaac, Paz-Rojas, Elier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962412/
https://www.ncbi.nlm.nih.gov/pubmed/35203631
http://dx.doi.org/10.3390/biomedicines10020422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962412/
https://www.ncbi.nlm.nih.gov/pubmed/35203631
http://dx.doi.org/10.3390/biomedicines10020422

Ejemplares similares