Cargando…

Development of a High-Throughput Calcium Mobilization Assay for CCR6 Receptor Coupled to Hydrolase Activity Readout

CCR6 is a chemokine receptor highly implicated in inflammatory diseases and could be a potential therapeutic target; however, no therapeutic agents targeting CCR6 have progressed into clinical evaluation. Development of a high-throughput screening assay for CCR6 should facilitate the identification...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gómez-Melero, Sara, García-Maceira, Fé Isabel, García-Maceira, Tania, Luna-Guerrero, Verónica, Montero-Peñalvo, Gracia, Caballero-Villarraso, Javier, Túnez, Isaac, Paz-Rojas, Elier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962412/ https://www.ncbi.nlm.nih.gov/pubmed/35203631 http://dx.doi.org/10.3390/biomedicines10020422

Ejemplares similares

Amino terminal recognition by a CCR6 chemokine receptor antibody blocks CCL20 signaling and IL-17 expression via β-arrestin
por: Gómez-Melero, Sara, et al.
Publicado: (2021)

Highly enhanced ELISA sensitivity using acetylated chitosan surfaces
por: García-Maceira, Tania, et al.
Publicado: (2020)

Covalent Immobilization of Antibodies through Tetrazine-TCO Reaction to Improve Sensitivity of ELISA Technique
por: García-Maceira, Tania, et al.
Publicado: (2021)

CCR6 as a Potential Target for Therapeutic Antibodies for the Treatment of Inflammatory Diseases
por: Gómez-Melero, Sara, et al.
Publicado: (2023)

Clinical and Neurochemical Effects of Transcranial Magnetic Stimulation (TMS) in Multiple Sclerosis: A Study Protocol for a Randomized Clinical Trial
por: Agüera, Eduardo, et al.
Publicado: (2020)

Extra-Virgin Olive Oil Modifies the Changes Induced in Non-Nervous Organs and Tissues by Experimental Autoimmune Encephalomyelitis Models
por: Conde, Cristina, et al.
Publicado: (2019)

SARS-CoV-2 infection in multiple sclerosis patients: interaction with treatments, adjuvant therapies, and vaccines against COVID-19
por: Muñoz-Jurado, Ana, et al.
Publicado: (2022)

Melatonin and multiple sclerosis: antioxidant, anti-inflammatory and immunomodulator mechanism of action
por: Muñoz-Jurado, Ana, et al.
Publicado: (2022)

Impact of Repetitive Transcranial Magnetic Stimulation on Neurocognition and Oxidative Stress in Relapsing-Remitting Multiple Sclerosis: A Case Report
por: Agüera, Eduardo, et al.
Publicado: (2020)

Ajedrez : variantes para la vida /
por: Maceira Moya, Nery

El sueño y la práctica de sí : pedagogía feminista : una propuesta
por: Maceira Ochoa, Luz
Publicado: (2008)

Cardiovascular magnetic resonance in systemic hypertension
por: Maceira, Alicia M, et al.
Publicado: (2012)

Reducing the equity gap in child health care and health system reforms in Latin America
por: Maceira, Daniel, et al.
Publicado: (2022)

Short-term variation of HIV tropism readouts in the absence of CCR5 antagonists
por: Brumme, CJ, et al.
Publicado: (2010)

Foot and ankle tendoscopies: current concepts review
por: Monteagudo, Manuel, et al.
Publicado: (2016)

Analysis of interobserver reproducibility in grading histological patterns of dysplastic nevi()
por: Nobre, Aretha Brito, et al.
Publicado: (2013)

The Panther Fusion System with Open Access Functionality for Laboratory-Developed Tests for Influenza A Virus Subtyping
por: Stellrecht, Kathleen A., et al.
Publicado: (2020)

Impact of the SARS-CoV-2 pandemic on the diagnosis of primary cutaneous melanoma at a University Hospital in Rio de Janeiro()
por: Barcaui, Carlos Baptista, et al.
Publicado: (2022)

Is really epicardial fat a new marker of cardiovascular risk? A case-control cardiac magnetic resonance study
por: Igual-Muñoz, Begoña, et al.
Publicado: (2015)

Loose Anchoring of Anagen Hairs and Pili Torti due to Erlotinib
por: Pirmez, Rodrigo, et al.
Publicado: (2016)

Understanding inequities in health and health systems in Latin America and the Caribbean: a thematic series
por: Ruano, Ana Lorena, et al.
Publicado: (2021)

Miliary Osteoma Cutis: A Case Report
por: Aguinaga, Felipe, et al.
Publicado: (2014)

Parallel ridge pattern on dermoscopy: observation in non-melanoma cases
por: Fracaroli, Tainá Scalfoni, et al.
Publicado: (2013)

Wearable technology in stroke rehabilitation: towards improved diagnosis and treatment of upper-limb motor impairment
por: Maceira-Elvira, Pablo, et al.
Publicado: (2019)

Roll Angle Estimation of a Motorcycle through Inertial Measurements
por: Maceira, Diego, et al.
Publicado: (2021)

Reference values for regional and global myocardial T2 mapping with cardiovascular magnetic resonance at 1.5T and 3T
por: Maceira, Alicia M, et al.
Publicado: (2015)

Trichoscopy of Noncicatricial Pressure-induced Alopecia Resembling Alopecia Areata
por: Papaiordanou, Francine, et al.
Publicado: (2016)

Characterization of left and right atrial function in healthy volunteers by cardiovascular magnetic resonance
por: Maceira, Alicia M., et al.
Publicado: (2016)

Automated Real-Time PCR Detection of Tickborne Diseases Using the Panther Fusion Open Access System
por: Stellrecht, Kathleen A., et al.
Publicado: (2022)

Neural Network Aided Detection of Huntington Disease
por: Alfonso Perez, Gerardo, et al.
Publicado: (2022)

An Entropy Approach to Multiple Sclerosis Identification
por: Perez, Gerardo Alfonso, et al.
Publicado: (2022)

Variants translating reduced expression of the beta estrogen receptor gene were associated with increased carotid intima media thickness: A cross-sectional study in late postmenopausal women
por: Cano-Marquina, Antonio-Jorge, et al.
Publicado: (2021)

Reference ventricular dimensions and function parameters by cardiovascular magnetic resonance in highly trained Caucasian athletes
por: Maceira, Alicia M., et al.
Publicado: (2023)

Casos prácticos sobre análisis de inversiones y financiación de pymes : desafiar la miopía empresarial /
por: Ortigueira Bobillo, José Manuel, et al.
Publicado: (2004)

Follicular red dots: a normal trichoscopy feature in patients with pigmentary disorders?*
por: Rodrigo, Pirmez, et al.
Publicado: (2013)

Comparison of three commercial RT-PCR systems for the detection of respiratory viruses
por: Butt, S.A., et al.
Publicado: (2014)

Primary systemic amyloidosis, acquired cutis laxa and cutaneous mucinosis in a patient with multiple myeloma
por: Lavorato, Fernanda Guedes, et al.
Publicado: (2013)

Discovery of Bile Salt Hydrolase Inhibitors Using an Efficient High-Throughput Screening System
por: Smith, Katie, et al.
Publicado: (2014)

Development of a High Throughput Platform for Screening Glycoside Hydrolases Based on Oxime-NIMS
por: Deng, Kai, et al.
Publicado: (2015)

Cardiovascular Magnetic Resonance and prognosis in cardiac amyloidosis
por: Maceira, Alicia M, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_s6ilal9uoch0lpf693g0hnvpv2