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Genome-wide phenotypic RNAi screen in the Drosophila wing: global parameters

We have screened a collection of UAS-RNAi lines targeting 10,920 Drosophila protein-coding genes for phenotypes in the adult wing. We identified 3653 genes (33%) whose knockdown causes either larval/pupal lethality or a mutant phenotype affecting the formation of a normal wing. The most frequent phe...

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Detalles Bibliográficos
Autores principales: López-Varea, Ana, Ostalé, Cristina M, Vega-Cuesta, Patricia, Ruiz-Gómez, Ana, Organista, María F, Martín, Mercedes, Hevia, Covadonga F, Molnar, Cristina, de Celis, Jesús, Culi, Joaquim, Esteban, Nuria, de Celis, Jose F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962446/
https://www.ncbi.nlm.nih.gov/pubmed/34599819
http://dx.doi.org/10.1093/g3journal/jkab351