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Epigenome-wide DNA methylation profiling of conditioned pain modulation in individuals with non-specific chronic low back pain

BACKGROUND: The pathoanatomic cause of chronic low back pain (cLBP) cannot be identified for up to 90% of individuals. However, dysfunctional processing of endogenous nociceptive input, measured as conditioned pain modulation (CPM), has been associated with cLBP and may involve changes in neuronal g...

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Detalles Bibliográficos
Autores principales: Goodin, Burel R., Overstreet, Demario S., Penn, Terence M., Bakshi, Rahm, Quinn, Tammie L., Sims, Andrew, Ptacek, Travis, Jackson, Pamela, Long, D. Leann, Aroke, Edwin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962463/
https://www.ncbi.nlm.nih.gov/pubmed/35346352
http://dx.doi.org/10.1186/s13148-022-01265-z