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Epigenome-wide DNA methylation profiling of conditioned pain modulation in individuals with non-specific chronic low back pain
BACKGROUND: The pathoanatomic cause of chronic low back pain (cLBP) cannot be identified for up to 90% of individuals. However, dysfunctional processing of endogenous nociceptive input, measured as conditioned pain modulation (CPM), has been associated with cLBP and may involve changes in neuronal g...
Autores principales: | Goodin, Burel R., Overstreet, Demario S., Penn, Terence M., Bakshi, Rahm, Quinn, Tammie L., Sims, Andrew, Ptacek, Travis, Jackson, Pamela, Long, D. Leann, Aroke, Edwin N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962463/ https://www.ncbi.nlm.nih.gov/pubmed/35346352 http://dx.doi.org/10.1186/s13148-022-01265-z |
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