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tiRNA-Val promotes angiogenesis via Sirt1–Hif-1α axis in mice with diabetic retinopathy

BACKGROUND: Diabetic retinopathy (DR) is a specific microvascular complication arising from diabetes, and its pathogenesis is not completely understood. tRNA-derived stress-induced RNAs (tiRNAs), a new type of small noncoding RNA generated by specific cleavage of tRNAs, has become a promising target...

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Detalles Bibliográficos
Autores principales: Xu, Yan, Zou, Haidong, Ding, Qi, Zou, Yuelan, Tang, Chun, Lu, Yuyu, Xu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962541/
https://www.ncbi.nlm.nih.gov/pubmed/35346383
http://dx.doi.org/10.1186/s40659-022-00381-7