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An NF-κB/OVOL2 circuit regulates glucose import and cell survival in non-small cell lung cancer

BACKGROUND: Tumor cells tend to utilize glycolysis rather than aerobic respiration even under aerobic conditions. OVOL2, an inhibitory C2H2 zinc finger transcription factor, is a potential tumor suppressor in cancers. However, the association between OVOL2 and tumor energy metabolism is unknown. MET...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Geng, Guo-Jun, Guo, Jian-Guang, Mi, Yan-Jun, Zhu, Xiao-Lei, Li, Ning, Liu, Hong-Ming, Lin, Jun-Feng, Wang, Jian-Weng, Zhao, Guang, Ye, Guan-Zhi, Li, Bo-An, Luo, Qi-Cong, Jiang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962559/
https://www.ncbi.nlm.nih.gov/pubmed/35346238
http://dx.doi.org/10.1186/s12964-022-00845-z