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Anomalous Levels of CD47/Signal Regulatory Protein Alpha in the Hippocampus Lead to Excess Microglial Engulfment in Mouse Model of Perioperative Neurocognitive Disorders

BACKGROUND: Perioperative neurocognitive disorders (PNDs) are common complications of surgical patients, which can lead to prolonged hospitalization, increased complications, and decreased independence and quality of life. However, the underlying molecular mechanisms of PND remain largely obscure. M...

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Detalles Bibliográficos
Autores principales: Shui, Min, Sun, Yi, Lin, Dandan, Xue, Ziyi, Liu, Jianhui, Wu, Anshi, Wei, Changwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962642/
https://www.ncbi.nlm.nih.gov/pubmed/35360151
http://dx.doi.org/10.3389/fnins.2022.788675