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Single-Molecule Detection of Nucleic Acids via Liposome Signal Amplification in Mass Spectrometry

A single-molecule detection method was developed for nucleic acids based on mass spectrometry counting single liposome particles. Before the appearance of symptoms, a negligible amount of nucleic acids and biomarkers for the clinical diagnosis of the disease were already present. However, it is diff...

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Detalles Bibliográficos
Autores principales: Lin, Xiangcheng, Zhao, Mengmeng, Li, Mingyue, Long, Juan, Zhang, Jing, Yu, Fang, Xu, Fen, Sun, Lixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963037/
https://www.ncbi.nlm.nih.gov/pubmed/35214249
http://dx.doi.org/10.3390/s22041346