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Pre-Clinical Proof of Concept: Intra-Carotid Injection of Autologous CD34-Positive Cells for Chronic Ischemic Stroke

This study was conducted to evaluate the safety and efficacy of human peripheral blood CD34 positive (CD34(+)) cells transplanted into a murine chronic stroke model to obtain pre-clinical proof of concept, prior to clinical testing. Granulocyte colony stimulating factor (G-CSF) mobilized human CD34(...

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Detalles Bibliográficos
Autores principales: Ogawa, Yuko, Okinaka, Yuka, Kikuchi-Taura, Akie, Saino, Orie, Tani-Yokoyama, Ayumi, Masuda, Satoru, Komatsu-Horii, Miki, Ikemoto, Yoshihiko, Kawamoto, Atsuhiko, Fukushima, Masanori, Taguchi, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963182/
https://www.ncbi.nlm.nih.gov/pubmed/35360717
http://dx.doi.org/10.3389/fmed.2022.681316