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Increased Expression of Viral Sensor MDA5 in Pancreatic Islets and in Hormone-Negative Endocrine Cells in Recent Onset Type 1 Diabetic Donors

The interaction between genetic and environmental factors determines the development of type 1 diabetes (T1D). Some viruses are capable of infecting and damaging pancreatic β-cells, whose antiviral response could be modulated by specific viral RNA receptors and sensors such as melanoma differentiati...

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Detalles Bibliográficos
Autores principales: Nigi, Laura, Brusco, Noemi, Grieco, Giuseppina E., Fignani, Daniela, Licata, Giada, Formichi, Caterina, Aiello, Elena, Marselli, Lorella, Marchetti, Piero, Krogvold, Lars, Jorgensen, Knut Dahl, Sebastiani, Guido, Dotta, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963204/
https://www.ncbi.nlm.nih.gov/pubmed/35359976
http://dx.doi.org/10.3389/fimmu.2022.833141