Effects of Lysine N-ζ-Methylation in Ultrashort Tetrabasic Lipopeptides (UTBLPs) on the Potentiation of Rifampicin, Novobiocin, and Niclosamide in Gram-Negative Bacteria

Outer membrane (OM) drug impermeability typically associated with a molecular weight above 600 Da and high hydrophobicity prevents accumulation of many antibiotics in Gram-negative bacteria (GNB). Previous studies have shown that ultrashort tetrabasic lipopeptides (UTBLPs) containing multiple lysine...

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Detalles Bibliográficos
Autores principales: Schweizer, Linus, Ramirez, Danyel, Schweizer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963254/
https://www.ncbi.nlm.nih.gov/pubmed/35326798
http://dx.doi.org/10.3390/antibiotics11030335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963254/
https://www.ncbi.nlm.nih.gov/pubmed/35326798
http://dx.doi.org/10.3390/antibiotics11030335

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