Aldosterone-Induced Sarco/Endoplasmic Reticulum Ca(2+) Pump Upregulation Counterbalances Ca(v)1.2-Mediated Ca(2+) Influx in Mesenteric Arteries

In mesenteric arteries (MAs), aldosterone (ALDO) binds to the endogenous mineralocorticoid receptor (MR) and increases the expression of the voltage-gated L-type Ca(v)1.2 channel, an essential ion channel for vascular contraction, sarcoplasmic reticulum (SR) Ca(2+) store refilling, and Ca(2+) spark...

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Detalles Bibliográficos
Autores principales: Salazar-Enciso, Rogelio, Guerrero-Hernández, Agustín, Gómez, Ana M., Benitah, Jean-Pierre, Rueda, Angélica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963271/
https://www.ncbi.nlm.nih.gov/pubmed/35360237
http://dx.doi.org/10.3389/fphys.2022.834220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963271/
https://www.ncbi.nlm.nih.gov/pubmed/35360237
http://dx.doi.org/10.3389/fphys.2022.834220

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