Knowledge-Driven Approaches to Create the MTox700+ Metabolite Panel for Predicting Toxicity

Endogenous metabolite levels describe the molecular phenotype that is most downstream from chemical exposure. Consequently, quantitative changes in metabolite levels have the potential to predict mode-of-action and adversity, with regulatory toxicology predicated on the latter. However, toxicity-rel...

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Detalles Bibliográficos
Autores principales: Sostare, Elena, Lawson, Thomas N, Saunders, Lucy R, Colbourne, John K, Weber, Ralf J M, Sobanski, Tomasz, Viant, Mark R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963288/
https://www.ncbi.nlm.nih.gov/pubmed/35094093
http://dx.doi.org/10.1093/toxsci/kfac007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963288/
https://www.ncbi.nlm.nih.gov/pubmed/35094093
http://dx.doi.org/10.1093/toxsci/kfac007

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