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ABlooper: fast accurate antibody CDR loop structure prediction with accuracy estimation

MOTIVATION: Antibodies are a key component of the immune system and have been extensively used as biotherapeutics. Accurate knowledge of their structure is central to understanding their antigen-binding function. The key area for antigen binding and the main area of structural variation in antibodie...

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Detalles Bibliográficos
Autores principales: Abanades, Brennan, Georges, Guy, Bujotzek, Alexander, Deane, Charlotte M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963302/
https://www.ncbi.nlm.nih.gov/pubmed/35099535
http://dx.doi.org/10.1093/bioinformatics/btac016