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Current structure predictors are not learning the physics of protein folding
SUMMARY: Motivation. Predicting the native state of a protein has long been considered a gateway problem for understanding protein folding. Recent advances in structural modeling driven by deep learning have achieved unprecedented success at predicting a protein’s crystal structure, but it is not cl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963306/ https://www.ncbi.nlm.nih.gov/pubmed/35099504 http://dx.doi.org/10.1093/bioinformatics/btab881 |