SCONCE: a method for profiling copy number alterations in cancer evolution using single-cell whole genome sequencing

MOTIVATION: Copy number alterations (CNAs) are a significant driver in cancer growth and development, but remain poorly characterized on the single cell level. Although genome evolution in cancer cells is Markovian through evolutionary time, CNAs are not Markovian along the genome. However, existing...

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Detalles Bibliográficos
Autores principales: Hui, Sandra, Nielsen, Rasmus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963318/
https://www.ncbi.nlm.nih.gov/pubmed/35080614
http://dx.doi.org/10.1093/bioinformatics/btac041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963318/
https://www.ncbi.nlm.nih.gov/pubmed/35080614
http://dx.doi.org/10.1093/bioinformatics/btac041

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