A data-adaptive Bayesian regression approach for polygenic risk prediction

MOTIVATION: Polygenic risk score (PRS) has been widely exploited for genetic risk prediction due to its accuracy and conceptual simplicity. We introduce a unified Bayesian regression framework, NeuPred, for PRS construction, which accommodates varying genetic architectures and improves overall predi...

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Detalles Bibliográficos
Autores principales: Song, Shuang, Hou, Lin, Liu, Jun S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963326/
https://www.ncbi.nlm.nih.gov/pubmed/35020805
http://dx.doi.org/10.1093/bioinformatics/btac024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963326/
https://www.ncbi.nlm.nih.gov/pubmed/35020805
http://dx.doi.org/10.1093/bioinformatics/btac024

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