Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics

This study aimed to investigate the effects and underlying mechanisms of tormentic acid (TA) on carbon tetrachloride (CCl(4))-induced liver fibrosis in rats. The rats were intragastrically administered with 50% CCl(4) for 9 weeks to induce hepatic fibrosis, followed by various agents for 6 weeks. Tr...

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Detalles Bibliográficos
Autores principales: Lin, Xing, Wei, Yuanyuan, Li, Yan, Xiong, Yuhua, Fang, Bin, Li, Cuiyu, Huang, Quanfang, Huang, Renbin, Wei, Jinbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963336/
https://www.ncbi.nlm.nih.gov/pubmed/35359829
http://dx.doi.org/10.3389/fphar.2022.801982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963336/
https://www.ncbi.nlm.nih.gov/pubmed/35359829
http://dx.doi.org/10.3389/fphar.2022.801982

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