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Mitochondrial Displacement Loop Region SNPs Modify Sjögren’s Syndrome Development by Regulating Cytokines Expression in Female Patients

Mitochondrial dysfunction could induce innate immune response with cytokines releasing to initiate Sjögren’s syndrome (SS) onset. Single nucleotide polymorphisms (SNPs) in the mitochondrial displacement loop (D-loop) and mitochondrial DNA (mtDNA) copy number of female SS patients were evaluated for...

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Detalles Bibliográficos
Autores principales: Zhao, Yufei, Peng, Chenxing, Zhang, Jingjing, Lai, Ruixue, Zhang, Xiaoyun, Guo, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963357/
https://www.ncbi.nlm.nih.gov/pubmed/35360865
http://dx.doi.org/10.3389/fgene.2022.847521