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The Slack Channel Deletion Causes Mechanical Pain Hypersensitivity in Mice

The role of the Slack (also known as Slo2.2, K(Na)1.1, or KCNT1) channel in pain-sensing is still in debate on which kind of pain it regulates. In the present study, we found that the Slack(–/–) mice exhibited decreased mechanical pain threshold but normal heat and cold pain sensitivity. Subsequentl...

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Detalles Bibliográficos
Autores principales: Liu, Ye, Zhang, Fang-Fang, Song, Ying, Wang, Ran, Zhang, Qi, Shen, Zhong-Shan, Zhang, Fei-Fei, Zhong, Dan-Ya, Wang, Xiao-Hui, Guo, Qing, Tang, Qiong-Yao, Zhang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963359/
https://www.ncbi.nlm.nih.gov/pubmed/35359569
http://dx.doi.org/10.3389/fnmol.2022.811441