Cargando…

Extracellular vesicles from hypoxia-preconditioned mesenchymal stem cells alleviates myocardial injury by targeting thioredoxin-interacting protein-mediated hypoxia-inducible factor-1α pathway

BACKGROUND: Extracellular vesicles (EVs) derived from hypoxia-preconditioned (HP) mesenchymal stem cells (MSCs) have better cardioprotective effects against myocardial infarction (MI) in the early stage than EVs isolated from normoxic (NC)-MSCs. However, the cardioprotective mechanisms of HP-EVs are...

Descripción completa

Detalles Bibliográficos
Autores principales: Mao, Cheng-Yu, Zhang, Tian-Tian, Li, Dong-Jiu, Zhou, En, Fan, Yu-Qi, He, Qing, Wang, Chang-Qian, Zhang, Jun-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963381/
https://www.ncbi.nlm.nih.gov/pubmed/35432732
http://dx.doi.org/10.4252/wjsc.v14.i2.183