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Extracellular vesicles from hypoxia-preconditioned mesenchymal stem cells alleviates myocardial injury by targeting thioredoxin-interacting protein-mediated hypoxia-inducible factor-1α pathway
BACKGROUND: Extracellular vesicles (EVs) derived from hypoxia-preconditioned (HP) mesenchymal stem cells (MSCs) have better cardioprotective effects against myocardial infarction (MI) in the early stage than EVs isolated from normoxic (NC)-MSCs. However, the cardioprotective mechanisms of HP-EVs are...
Autores principales: | Mao, Cheng-Yu, Zhang, Tian-Tian, Li, Dong-Jiu, Zhou, En, Fan, Yu-Qi, He, Qing, Wang, Chang-Qian, Zhang, Jun-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963381/ https://www.ncbi.nlm.nih.gov/pubmed/35432732 http://dx.doi.org/10.4252/wjsc.v14.i2.183 |
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