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Computational mining of MHC class II epitopes for the development of universal immunogenic proteins

The human leukocyte antigen (HLA) gene complex, one of the most diverse gene complexes found in the human genome, largely dictates how our immune systems recognize pathogens. Specifically, HLA genetic variability has been linked to vaccine effectiveness in humans and it has likely played some role i...

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Detalles Bibliográficos
Autores principales: Saylor, Kyle, Donnan, Ben, Zhang, Chenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963548/
https://www.ncbi.nlm.nih.gov/pubmed/35349604
http://dx.doi.org/10.1371/journal.pone.0265644