Cargando…

TET2-mediated epigenetic reprogramming of breast cancer cells impairs lysosome biogenesis

Methylation and demethylation of cytosines in DNA are believed to act as keystones of cell-specific gene expression by controlling the chromatin structure and accessibility to transcription factors. Cancer cells have their own transcriptional programs, and we sought to alter such a cancer-specific p...

Descripción completa

Detalles Bibliográficos
Autores principales: Laurent, Audrey, Madigou, Thierry, Bizot, Maud, Turpin, Marion, Palierne, Gaëlle, Mahé, Elise, Guimard, Sarah, Métivier, Raphaël, Avner, Stéphane, Le Péron, Christine, Salbert, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963717/
https://www.ncbi.nlm.nih.gov/pubmed/35351824
http://dx.doi.org/10.26508/lsa.202101283