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TET2-mediated epigenetic reprogramming of breast cancer cells impairs lysosome biogenesis
Methylation and demethylation of cytosines in DNA are believed to act as keystones of cell-specific gene expression by controlling the chromatin structure and accessibility to transcription factors. Cancer cells have their own transcriptional programs, and we sought to alter such a cancer-specific p...
Autores principales: | Laurent, Audrey, Madigou, Thierry, Bizot, Maud, Turpin, Marion, Palierne, Gaëlle, Mahé, Elise, Guimard, Sarah, Métivier, Raphaël, Avner, Stéphane, Le Péron, Christine, Salbert, Gilles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963717/ https://www.ncbi.nlm.nih.gov/pubmed/35351824 http://dx.doi.org/10.26508/lsa.202101283 |
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