Knockdown of AKR1C3 Promoted Sorafenib Sensitivity Through Inhibiting the Phosphorylation of AKT in Hepatocellular Carcinoma

BACKGROUND: Sorafenib, which can induce ferroptosis, is a multikinase inhibitor for enhancing survival in advanced hepatocellular carcinoma (HCC). However, a considerable challenge for the treatment of HCC is sorafenib resistance. Therefore, targeting the relationship between sorafenib resistance an...

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Detalles Bibliográficos
Autores principales: Zheng, Jia, Yang, Zhihong, Li, Yanlei, Yang, Li, Yao, Ruili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963762/
https://www.ncbi.nlm.nih.gov/pubmed/35359392
http://dx.doi.org/10.3389/fonc.2022.823491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963762/
https://www.ncbi.nlm.nih.gov/pubmed/35359392
http://dx.doi.org/10.3389/fonc.2022.823491

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