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Variation of Positive Predictive Values of Fecal Immunochemical Tests by Polygenic Risk Score in a Large Screening Cohort

Prevalence of colorectal neoplasms varies by polygenic risk scores (PRS). We aimed to assess to what extent a PRS might be relevant for defining personalized cutoff values for fecal immunochemical tests (FITs) in colorectal cancer screening. METHODS: Among 5,306 participants of screening colonoscopy...

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Detalles Bibliográficos
Autores principales: Niedermaier, Tobias, Balavarca, Yesilda, Gies, Anton, Weigl, Korbinian, Guo, Feng, Alwers, Elizabeth, Hoffmeister, Michael, Brenner, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963839/
https://www.ncbi.nlm.nih.gov/pubmed/35060941
http://dx.doi.org/10.14309/ctg.0000000000000458