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Variation of Positive Predictive Values of Fecal Immunochemical Tests by Polygenic Risk Score in a Large Screening Cohort
Prevalence of colorectal neoplasms varies by polygenic risk scores (PRS). We aimed to assess to what extent a PRS might be relevant for defining personalized cutoff values for fecal immunochemical tests (FITs) in colorectal cancer screening. METHODS: Among 5,306 participants of screening colonoscopy...
Autores principales: | Niedermaier, Tobias, Balavarca, Yesilda, Gies, Anton, Weigl, Korbinian, Guo, Feng, Alwers, Elizabeth, Hoffmeister, Michael, Brenner, Hermann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963839/ https://www.ncbi.nlm.nih.gov/pubmed/35060941 http://dx.doi.org/10.14309/ctg.0000000000000458 |
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