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Effects of Receptor Specificity and Conformational Stability of Influenza A Virus Hemagglutinin on Infection and Activation of Different Cell Types in Human PBMCs

Humans can be infected by zoonotic avian, pandemic and seasonal influenza A viruses (IAVs), which differ by receptor specificity and conformational stability of their envelope glycoprotein hemagglutinin (HA). It was shown that receptor specificity of the HA determines the tropism of IAVs to human ai...

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Detalles Bibliográficos
Autores principales: Dorna, Jens, Kaufmann, Andreas, Bockmann, Viktoria, Raifer, Hartmann, West, Johanna, Matrosovich, Mikhail, Bauer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963867/
https://www.ncbi.nlm.nih.gov/pubmed/35359920
http://dx.doi.org/10.3389/fimmu.2022.827760