Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling

Elevations in plasma phosphate concentrations (hyperphosphatemia) occur in chronic kidney disease (CKD), in certain genetic disorders, and following the intake of a phosphate-rich diet. Whether hyperphosphatemia and/or associated changes in metabolic regulators, including elevations of fibroblast gr...

Descripción completa

Detalles Bibliográficos
Autores principales: Czaya, Brian, Heitman, Kylie, Campos, Isaac, Yanucil, Christopher, Kentrup, Dominik, Westbrook, David, Gutierrez, Orlando, Babitt, Jodie L, Jung, Grace, Salusky, Isidro B, Hanudel, Mark, Faul, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963881/
https://www.ncbi.nlm.nih.gov/pubmed/35302487
http://dx.doi.org/10.7554/eLife.74782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963881/
https://www.ncbi.nlm.nih.gov/pubmed/35302487
http://dx.doi.org/10.7554/eLife.74782

Ejemplares similares