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Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling
Elevations in plasma phosphate concentrations (hyperphosphatemia) occur in chronic kidney disease (CKD), in certain genetic disorders, and following the intake of a phosphate-rich diet. Whether hyperphosphatemia and/or associated changes in metabolic regulators, including elevations of fibroblast gr...
Autores principales: | Czaya, Brian, Heitman, Kylie, Campos, Isaac, Yanucil, Christopher, Kentrup, Dominik, Westbrook, David, Gutierrez, Orlando, Babitt, Jodie L, Jung, Grace, Salusky, Isidro B, Hanudel, Mark, Faul, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963881/ https://www.ncbi.nlm.nih.gov/pubmed/35302487 http://dx.doi.org/10.7554/eLife.74782 |
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