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Persistent cell migration emerges from a coupling between protrusion dynamics and polarized trafficking

Migrating cells present a variety of paths, from random to highly directional ones. While random movement can be explained by basal intrinsic activity, persistent movement requires stable polarization. Here, we quantitatively address emergence of persistent migration in (hTERT)–immortalizedRPE1 (ret...

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Detalles Bibliográficos
Autores principales: Vaidžiulytė, Kotryna, Macé, Anne-Sophie, Battistella, Aude, Beng, William, Schauer, Kristine, Coppey, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963884/
https://www.ncbi.nlm.nih.gov/pubmed/35302488
http://dx.doi.org/10.7554/eLife.69229