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Knowledge Graphs for Indication Expansion: An Explainable Target-Disease Prediction Method

Indication expansion aims to find new indications for existing targets in order to accelerate the process of launching a new drug for a disease on the market. The rapid increase in data types and data sources for computational drug discovery has fostered the use of semantic knowledge graphs (KGs) fo...

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Detalles Bibliográficos
Autores principales: Gurbuz, Ozge, Alanis-Lobato, Gregorio, Picart-Armada, Sergio, Sun, Miao, Haslinger, Christian, Lawless, Nathan, Fernandez-Albert, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963915/
https://www.ncbi.nlm.nih.gov/pubmed/35360842
http://dx.doi.org/10.3389/fgene.2022.814093