Peripheral Neuropathy During Concomitant Administration of Proteasome Inhibitors and Factor Xa Inhibitors: Identifying the Likelihood of Drug-Drug Interactions

Backgrounds: Proteasome inhibitors (PI) cause toxic peripheral neuropathy (PN), which is one of the dose-limiting adverse events of these treatments. Recent preclinical studies find that factor Xa inhibitor (FXaI), rivaroxaban, promotes PN in animals receiving oxaliplatin. Cancer patients can receiv...

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Detalles Bibliográficos
Autores principales: Meng, Long, Huang, Jing, Qiu, Feng, Shan, Xuefeng, Chen, Lin, Sun, Shusen, Wang, Yuwei, Yang, Junqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963930/
https://www.ncbi.nlm.nih.gov/pubmed/35359859
http://dx.doi.org/10.3389/fphar.2022.757415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963930/
https://www.ncbi.nlm.nih.gov/pubmed/35359859
http://dx.doi.org/10.3389/fphar.2022.757415

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