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B Cell IL-4 Drives Th2 Responses In Vivo, Ameliorates Allograft Rejection, and Promotes Allergic Airway Disease

B cells can be polarized to express various cytokines. The roles of IFNγ and IL-10, expressed respectively by B effector 1 (Be1) and Bregs, have been established in pathogen clearance, tumor growth, autoimmunity and allograft rejection. However, the in vivo role of B cell IL-4, produced by Be2 cells...

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Detalles Bibliográficos
Autores principales: Song, Zhixing, Yuan, Wenjia, Zheng, Leting, Wang, Xingan, Kuchroo, Vijay K., Mohib, Kanishka, Rothstein, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963939/
https://www.ncbi.nlm.nih.gov/pubmed/35359977
http://dx.doi.org/10.3389/fimmu.2022.762390