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Continuous Activation of Dopamine Receptors Alleviates LPS-Induced Liver Injury in Mice via β-arrestin2 Dependent Akt/NF-κB Pathway

Many studies showed that dopamine receptors (DRs) agonists have anti-inflammatory effects. Rotigotine, a non-ergot dopamine receptor agonist, mainly actives DRD2/DRD3/DRD1. Rotigotine extended-release microspheres (RoMS) are a sustained-release formulation that can release sustainably rotigotine for...

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Detalles Bibliográficos
Autores principales: Li, Mingan, Zhang, Ce, Zhou, Lin, Sun, Xiaohui, Wang, Tian, Fu, Fenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963954/
https://www.ncbi.nlm.nih.gov/pubmed/35359858
http://dx.doi.org/10.3389/fphar.2022.853834