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Dietary Fiber as a Counterbalance to Age-Related Microglial Cell Dysfunction
With increasing age, microglia shift toward a pro-inflammatory phenotype that may predispose individuals to neurodegenerative disease. Because fiber fermentation in the colon produces bioactive short-chain fatty acids (SCFAs; e.g., acetate, butyrate, and propionate) that signal through the gut-brain...
Autores principales: | Vailati-Riboni, Mario, Rund, Laurie, Caetano-Silva, Maria Elisa, Hutchinson, Noah T., Wang, Selena S., Soto-Díaz, Katiria, Woods, Jeffrey A., Steelman, Andrew J., Johnson, Rodney W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964049/ https://www.ncbi.nlm.nih.gov/pubmed/35360677 http://dx.doi.org/10.3389/fnut.2022.835824 |
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